Loureirin B
CAS No. 119425-90-0
Loureirin B ( Loureirin B; LR-B; L B; LRB )
Catalog No. M17868 CAS No. 119425-90-0
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 132 | In Stock |
|
10MG | 196 | In Stock |
|
25MG | 332 | In Stock |
|
50MG | 489 | In Stock |
|
100MG | 698 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameLoureirin B
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NoteResearch use only, not for human use.
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Brief DescriptionLoureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.
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DescriptionLoureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.
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SynonymsLoureirin B; LR-B; L B; LRB
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number119425-90-0
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Formula Weight316.35
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Molecular FormulaC18H20O5
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Purity98%
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SolubilityDMSO : ≥ 150 mg/mL; 474.16 mM
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SMILESCOc1cc(c(c(c1)OC)CCC(=O)c1ccc(cc1)O)OC
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Chemical Name1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)propan-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bai X, et al. Loureirin B inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via TGF-β/Smad pathway. Exp Dermatol. 2015 May;24(5):355-60.
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