Loureirin B

CAS No. 119425-90-0

Loureirin B ( Loureirin B; LR-B; L B; LRB )

Catalog No. M17868 CAS No. 119425-90-0

Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 132 In Stock
10MG 196 In Stock
25MG 332 In Stock
50MG 489 In Stock
100MG 698 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Loureirin B
  • Note
    Research use only, not for human use.
  • Brief Description
    Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.
  • Description
    Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.
  • Synonyms
    Loureirin B; LR-B; L B; LRB
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    119425-90-0
  • Formula Weight
    316.35
  • Molecular Formula
    C18H20O5
  • Purity
    98%
  • Solubility
    DMSO : ≥ 150 mg/mL; 474.16 mM
  • SMILES
    COc1cc(c(c(c1)OC)CCC(=O)c1ccc(cc1)O)OC
  • Chemical Name
    1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)propan-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bai X, et al. Loureirin B inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via TGF-β/Smad pathway. Exp Dermatol. 2015 May;24(5):355-60.
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